Douglas S. English

Department Chair,
Associate Professor


  • Ph.D., Iowa State University
  • B.S. University of Missouri, Kansas City

Principal Research Interests

  • Nanomaterials
  • Self-Assembly
  • Biophysics
  • Fluorescence Detection and Spectroscopy


  1. Exploring one-state downhill protein folding in single molecules. J. W. Liu, L. Campos, M. Cerminara, X. Wang,R. Ramanathan, D. S. English and V. Munoz, Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 179-184.
  2. Single-Molecule Colocalization Studies Shed Light on the Idea of Fully Emitting versus Dark Single Quantum Dots. T. Pons, I. L. Medintz, D. Farrell, X. Wang, A. F. Grimes, D. S. English, L. Berti, H. Mattoussi, Small 2011, 7, 2101-2108.
  3. A photoprotection strategy for microsecond-resolution single-molecule fluorescence spectroscopy. L. A. Campos, J. W. Liu, X. Wang, R. Ramanathan, D. S. English, and V. Munoz, Nat Methods 2011, 8, 143-146.
  4. The Role of Charge in the Surfactant-Assisted Stabilization of the Natural Product Curcumin. Z. F. Wang, M. H. M. Leung, T. W. Kee and D. S. English, Langmuir 2010, 26, 5520-5526.
Proceedings and Book Chapters

3. Kenji Okamoto, Karthik Jayaraman, Sang Jun Son, Sang Bok Lee and Douglas S. English, 2004. "Wetting and Diffusion Phenomena in Silica Nanotubes" Dekker Encyclopedia of Nanoscience and Nanotechnology

2. D. S. English, J. A. Cunningham, S. C. Wehri, A. F. Petrik and K. Okamoto, 2004. "Single molecule studies of surface-induced secondary structure in a model peptide" SPIE proceedings series, 5513-32.

1. W. Losert, C. Poole, P. Bradford and D. English, 2004. "Shape deformations of giant unilamellar vesicles with a laser tweezer array." SPIE proceedings series, 5514.

All Publications

43. Goodson, K. A.; Wang, Z.; Haeusler, A. R.; Kahn, J. D.; English, D. S.: LacI-DNA-IPTG Loops: Equilibria among Conformations by Single-Molecule FRET. J. Phys. Chem. B. 2013, In Press.

42. Liu, J. W.; Campos, L. A.; Cerminara, M.; Wang, X.; Ramanathan, R.; English, D. S.; Munoz, V.: Exploring one-state downhill protein folding in single molecules. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 179-184.

41. Pons, T.; Medintz, I. L.; Farrell, D.; Wang, X.; Grimes, A. F.; English, D. S.; Berti, L.; Mattoussi, H.: Single-Molecule Colocalization Studies Shed Light on the Idea of Fully Emitting versus Dark Single Quantum Dots. Small 2011, 7, 2101-2108.

40. Campos, L.A.; Liu, J.; Wang, X.; Ramanatan, R.; English, D. S.; Munoz V.; 2011, "A photoprotection strategy for microsecond-resolution single molecule fluorescence spectroscopy." Nature Methods, 8, 143-146.

39. Wang, Z.; Leung, H. M.; Kee, T. W.; English, D. S.; 2010, "The Role of Charge in the Surfactant Assisted Stabilization of the Natural Product Curcumin." Langmuir, 26, 5520-5526.

38. Lioi, S. B.; Wang, X.; Islam, M.R.; English, D.S.; 2009, "Catanionic Surfactant Vesicles for Electrostatic Molecular Sequestration and Separation." Phys. Chem. Chem. Phys., DOI: 10.1039/B908523H.

37. Thomas, G. B.; Rader, L. H.; Park, J.; DeShong, P.; English, D. S.; 2009,"Carbohydrate Modified Catanionic Vesicles: Probing Multivalent Binding at the Bilayer Interface."J. Am. Chem. Soc.,131, 5471-5477.

36. Medintz, I. L.; Pons, T.; Trammell, S. A.; Grimes, A. F.; English, D. S.; Blanco-Canosa, S. B.; Dawson, P. E.; Mattoussi, H. , 2008,"Interactions between Redox Complexes and Semiconductor Quantum Dots Coupled Via a Peptide Bridge."J. Amer. Chem. Soc., 130, 16745-16756.

35. Dias, E. A.; Grimes, A. F.; English, D. S.; Kambhampati,P.; 2008,"Single Dot Spectroscopy of Two-Color Quantum Dot/Quantum Shell." J. Phys. Chem. C.,112, 14229-32.

34. Park, J.; Rader, L. H.;Thomas, G. B.; Danoff, E. J.; English, D. S.; DeShong, P., 2008,"Carbohydrate-functionalized Catanionic Surfactant Vesicles: Preparation and Lectin-Binding Studies."Soft Matter, 4, 1916-1921.

33. Pons, T.; Medintz, I.L.; Sapsford, K.E.; Higashiya, S. Grimes, A.F.; English, D.S.; Mattoussi, H., 2007,"On the quenching of semiconductor quantum dot photoluminescence by proximal gold nanoparticles ." Nano Letters, 7, 3157-3164.

32. Zhu, C.; Wu, L.-Q.; Wang, X.; Lee, J.-H.; English, D. S.; Ghodssi, R.; Raghavan, S. R.; Payne, G. F., 2007, "Reversible Vesicle Restraint in Response to Spatiotemporally Controlled Electrical Signals: A Bridge between Electrical and Chemical Signaling Modes." Langmuir,23, 286-91.

31. Medintz, I. L.; Berti, L.; Pons, T.; Grimes, A. F.; English, D. S.; Alessandrini, A.; Facci, P.; Mattoussi, H., 2007, "A Reactive Peptidic Linker for Self-Assembling Hybrid Quantum Dot-DNA Bioconjugates." Nano Letters,7, 1741-48.

30. Grimes, A. F.; Call, S. E.; Harbron, E. J.; English, D. S., 2007, "Wavelength-Resolved Studies of Förster Energy Transfer in Azobenzene-Modified Conjugated Polymers: The Competing Roles of Exciton Migration and Spectral Resonance." J. Phys. Chem. C.,111.

29. Danoff, E. J.; Wang, X.; Tung, S.-H.; Sinkov, N. A.; Kemme, A. M.; Raghavan, S. R.; English, D. S., 2007, "Surfactant Vesicles for High-Efficiency Capture and Separation of Charged Organic Solutes." Langmuir,23, 8965-71

28. Wang, X.; Danoff, E. J.; Sinkov, N. A.; Lee, J.-H.; Raghavan, S. R.; English, D. S., 2006, "Highly Efficient Capture and Long-Term Encapsulation of Dye by Catanionic Surfactant Vesicles." Langmuir,22, 6461-64.

27. Grimes, A. F.; Call, S. E.; Vicentia, D. A.; English, D. S.; Harbron, E. J., 2006, "Toward Efficient Photomodulation of Conjugated Polymer Emission: Optimizing Differential Energy Transfer in Azobenzene-Substituted PPV Derivatives." J. Phys. Chem. B.,110, 19183-90.

26. Pons, T.; Medintz, I. L.; Wang, X.; English, D. S.; Mattoussi, H., 2006, "Solution-Phase Single Quantum Dot Fluorescence Resonance Energy Transfer." J. Am. Chem. Soc.,128, 15324-31.

25. I. Koh, X Wang, B. Varughese L. Isaacs, S. Ehrman and D. S. English, 2006 "Preparation and Characterization of Antibody Labeled Magnetic Iron Oxide Nanoparticles for Bioseparations." J. Phys. Chem. B., 2006, 110, 1553-58.

24. English, D. S.; Luckett, C.; Jayaraman, K.; Lee, S. B.; Son, S. J.; Okamoto, K., 2006, "Solvent Behavior in Hydrophobic Silica Nanotubes." Mater. Res. Soc. Symp. Proc.,899E.

23. Jayaraman, K.; Okamoto, K.; Son, S. J.; Luckett, C.; Gopalani, A. H.; Lee, S. B.; English, D. S., 2005, "Observing Capillarity in Hydrophobic Silica Nanotubes." J. Am. Chem. Soc.,127, 17385-92.

22. M. Morgan, K. Okamoto, J. D. Kahn and D. S. English, 2005. "Single Molecule Spectroscopic Determination of Lac Repressor-DNA Loop Conformation." Biophysical Journal, 89, 2588-2596.

21. Li-Qun Wu, K. Lee, X. Wang, D. S. English, W. Losert, and G. F. Payne, 2005. "Chitosan-Mediated and Spatially Selective Electrodeposition of Nano-Scale Particles."Langmuir, 21 (8): 3641-3646.

20. Sivanesana, P., K. Okamoto, D. English, C. S. Lee and D. L. Devoe, 2005. "Polymer nanochannels fabricated by thermomechanical deformation for single molecule analysis." Analytical Chemistry, 77 (7); 2252-2258.

19. Okamoto, K., C. Shook, L. Bivona, S.B. Lee, and D.S. English, 2004. "Direct observation of wetting and diffusion in the hydrophobic interior of silica nanotubes.", Nano Letters, 4(2) p.233-239.

18. Jang, H., L.E. Pell, B.A. Korgel, and D.S. English, 2003. "Photoluminescence quenching of silicon nanoparticles in phospholipid vesicle bilayers." Journal of Photochemistry and Photobiology, A: Chemistry, 158(2-3): p. 111-117.

17. English, D.S., L.E. Pell, Z. Yu, P.F. Barbara, and B.A. Korgel, 2002. "Size tunable visible luminescence from individual organic monolayer stabilized silicon nanocrystal quantum dots." Nano Letters, 2(7): p. 681-685.

16. Kolosov, D., D.S. English, V. Bulovic, P.F. Barbara, S.R. Forrest, and M.E. Thompson, 2001. "Direct observation of structural changes in organic light emitting devices during degradation." Journal of Applied Physics, 90(7): p. 3242-3247.

15. English, D.S., E.J. Harbron, and P.F. Barbara, 2001. "Role of rare sites in single molecule spectroscopy measurements of spectral diffusion." Journal of Chemical Physics, 114(23): p. 10479-10485.

14. Whaley, S.R., D.S. English, E.L. Hu, P.F. Barbara, and A.M. Belcher, 2000. "Selection of peptides with semiconductor binding specificity for directed nanocrystal assembly." Nature, 405(6787): p. 665-668.

13. English, D.S., A. Furube, and P.F. Barbara, 2000. "Single-molecule spectroscopy in oxygen-depleted polymer films." Chemical Physics Letters, 2000. 324(1-3): p. 15-19.

12. English, D.S., E.J. Harbron, and P.F. Barbara, 2000. "Probing photoinduced intersystem crossing by two-color, double resonance single molecule spectroscopy." Journal of Physical Chemistry A, 104(40): p. 9057-9061.

11. Smirnov, A.V., K. Das, D.S. English, Z. Wan, G.A. Kraus, and J.W. Petrich, 1999. "Excited-state intramolecular H atom transfer of hypericin and hypocrellin A investigated by fluorescence upconversion." Journal of Physical Chemistry A, 103(40): p. 7949-7957.

10. English, D.S., R.T. Doyle, J.W. Petrich, and P.G. Haydon, 1999. "Subcellular distributions and excited-state processes of hypericin in neurons." Photochemistry and Photobiology, 69(3): p. 301-305.

9. Park, J., D.S. English, Y. Wannemuehler, S. Carpenter, and J.W. Petrich, 1998. "The role of oxygen in the antiviral activity of hypericin and hypocrellin." Photochemistry and Photobiology, 68(4): p. 593-597.

8. English, D.S., R.L. Rich, and J.W. Petrich, 1998. "Nonexponential fluorescence decay of 7-azatryptophan induced in a peptide environment." Photochemistry and Photobiology, 67(1): p. 76-83.

7. Smirnov, A.V., D.S. English, R.L. Rich, J. Lane, L. Teyton, A.W. Schwabacher, S. Luo, R.W. Thornburg, and J.W. Petrich, 1997. "Photophysics and biological applications of 7-azaindole and its analogs." Journal of Physical Chemistry B, 101(15): p. 2758-2769.

6. English, D.S., W. Zhang, G.A. Kraus, and J.W. Petrich, 1997. "Excited-state photophysics of hypericin and its hexamethoxy analog: Intramolecular proton transfer as a nonradiative process in hypericin." Journal of the American Chemical Society, 119(13): p. 2980-2986.

5. English, D.S., K. Das, J.M. Zenner, W. Zhang, G.A. Kraus, R.C. Larock, and J.W. Petrich, 1997. "Hypericin, hypocrellin, and model compounds: Primary photoprocesses of light-induced antiviral agents." Journal of Physical Chemistry A, 101(18): p. 3235-3240.

4. English, D.S., K. Das, K.D. Ashby, J. Park, J.W. Petrich, and E.W. Castner,1997. "Confirmation of excited-state proton transfer and ground-state heterogeneity in hypericin by fluorescence upconversion." Journal of the American Chemical Society, 119(48): p. 11585-11590.

3. Das, K., D.S. English, and J.W. Petrich, 1997. "Solvent dependence on the intramolecular excited-state proton or hydrogen atom transfer in hypocrellin." Journal of the American Chemical Society, 119(11): p. 2763-2764.

2. Das, K., D.S. English, and J.W. Petrich, 1997. "Deuterium isotope effect on the excited-state photophysics of hypocrellin: Evidence for proton or hydrogen atom transfer.",Journal of Physical Chemistry A, 101(18): p. 3241-3245.

1. Das, K., D.S. English, M.J. Fehr, A.V. Smirnov, and J.W. Petrich, 1996. "Excited-state processes in polycyclic quinones: The light- induced antiviral agent, hypocrellin, and a comparison with hypericin." Journal of Physical Chemistry, 1996. 100(46): p. 18275-18281.