His research is in the area of experimental particle and astroparticle physics, in the past he worked extensively on quark flavor physics by rare decays of hadrons, CP violation with Kaons, the study of nuclear states of matter and hadronic interaction physics. He was the co-spokesman of the Fermilab E907 experiment. He is also author of the book The Elusive Neutrino, and continues as editor of the Conference series on Hyperon, Charm and Beauty Hadrons, and has over 200 referred articles in physics research. His current experiments include neutrino experiments of NOvA and DUNE at Fermilab, and he is the PI of a new NASA project Neutrino Solar Orbiting Laboratory that aims to do unique neutrino science with a neutrino space-craft. Since 2018 he has been NASA Innovation Advanced Concept Fellow.