The Talent Search programs are educational opportunity outreach programs and are specifically designed to motivate and support students from disadvantaged backgrounds. TRiO includes six outreach and support programs targeted to serve and assist low-income, first-generation college students, and students with disabilities to progress through the academic pipeline from middle school to post baccalaureate programs. TRiO also includes a training program for directors and staff of TRiO projects and a dissemination partnership program to encourage the replication or adaptation of successful practices of TRiO projects at institutions and agencies that do not have TRiO grants.

Some of the programs that have been developed are National TRiO Day, which is a celebration for the accomplishments of the TRiO programs and students, Summer Enrichment Program which provides supplemental instruction in core learning areas and Campus visits.