Jeffrey V. May, PhD
Jeffrey V. May, PhD
Research Scientist, Department of Biological Sciences
Office: 438 Hubbard Hall
Lab: 437 Hubbard Hall
Phone: (316) 978-6177
Fax: (316) 378-3772
E-mail: jeffrey.may@wichita.edu
Adjunct Associate Professor, Dept. of Medical Sciences, School of Medicine-Wichita,
University of Kansas Medical Center, Wichita, Kansas
Education
Professional Experience
Research Interests
Current Grant Activity
Current Publications
Honors and Other Activities
Courses Previously Taught
Education
| University of Maine | B.S. | 1970 | Biochemistry |
| University of Rhode Island | Ph.D. | 1979 | Biochemistry |
| Duke University Medical Center | Postdoctoral Fellowship | 1979 - 1982 | Reproductive Biology |
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Professional Experience
| 2002 - 2009 | Associate Professor, Dept. of Biological Sciences, Wichita State University, Wichita, KS |
| 2002 - 2004 | Executive Director, H.L. Snyder Medical Research Institute, Winfield, KS |
| 1993 - 2002 | Scientific Director, The Women's Research Institute, Wichita, KS |
| 1987 - 2002 | Senior Scientist, The Women's Research Institute, Wichita, KS |
| 1991 - 2002 | Associate Professor, Dept. of Ob/Gyn, Un. of KS School of Medicine-Wichita, Wichita, KS |
| 1995 - 2002 | Adjunct Professor, Dept. of Biological Sciences, Wichita State University, Wichita, KS |
| 1988 - 1997 | Director, Assisted Reproductive Technology Lab, The Center for Reproductive Medicine, Univ. of KS School of Medicine-Wichita, Wichita, KS |
| 1987 - 1991 | Assistant Professor, Dept. of Ob/Gyn, Univ. of KS School of Medicine-Wichita, Wichita, KS |
| 1982 - 1987 | Assistant Professor of Ob/Gyn (non-tenure track) and Assistant Professor of Physiology, Duke University Medical Center, Durham, NC |
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Research Interests
I am a mammalian reproductive biologist with a fundamental interest in ovarian function. This includes: the mechanisms underlying folliculogenesis focusing on the role of somatic cells in regulating this process; factors governing early embryo development; clinical infertility; and ovarian cancer. I am part of a NIH-funded Program Project investigating the differential activity and function of human FSH glycoforms upon reproductive function and how these glycoforms change as a function of age. Numerous techniques are utilized to address the above research areas including primary cell culture, molecular biology, biochemistry, and morphological analysis.
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Current Grant Activity
| Grant #: 5P01-AG029531-07 [NIH, NIA] (Bousfield, PI) |
09/01/17 - 05/31/22 | Title: The Aging Pituitary/Gonadal Axis | $1,709,158 /5 yr |
Roles: Co-Leader, Core A-Administrative Core Leader, Core B - FSH Preparation, Purification and Analysis Laboratory |
| K-INBRE Core Facility Award | 05/10/19 - 04/30/20 | Title: WSU P01 Core Lab Cell Counter | $8,018 | Role: Principal Investigator |
| K-INBRE Core Facility Award | 05/01/17 - 04/30/18 | Title: WSU P01 Core Lab Ultralow -80C Freezer | $10,081 | Role: Principal Investigator |
| Grant #: 5P01-AG029531-02 [NIH, NIA] (Bousfield, PI) |
03/01/09 - 02/28/14 | Title: The Aging Pituitary/Gonadal Axis | $6,622,855 /5 yr |
Roles: Co-Leader, Core A-Administrative Core Leader, Core B - FSH Preparation, Purification and Analysis Laboratory |
|
K-INBRE Translational Parnershp Pair Grant |
04/01/12 - 03/31/13 |
Diagnostic Relevance of Human Urinary FSH Glycoform Assessment to Ovarian Aging |
$37,500 | Role: Principal Investigator |
| K-INBRE Core Facility Grant | 05/01/11 - 04/30/12 | Title: WSU P01 Core Lab Roller Bottle Incubator | $18,557 | Role: Principal Investigator |
| Grant #: 1G20RR031092-01 [NCRR] (Hendry, PI) |
07/01/10 - 06/30/11 | Title: Wichita State University Combined Core Facility Renovation Project | $2,109,094 /2 yr. |
Role: Grant Proposal Author & Project Manager. The application was organizae and written entirely by Dr. May who is responsible for progress and completion of the project. |
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Current Publications
- Bousfield, G. R., May, J. V., Davis, J. S., Dias, J. A., & Kumar, T. R. 2018. In vivo and in vitro impact of carbohydrate variation on follicle-stimulating hormone function. Front. Endocrinol., 9, 216.
- Wang, H., May, J., Shuai, B., May, J. V., Bousfield, G. R., & Kumar, T. R. 2016. Evaluation of in vivo bioactivities of recombiant hypo-(FSH21/18) and fully- (FSH24) glycosylated human FSH glycoforms in Fshb null mice. Mol. Cell. Endocrinol., 437, 224-236.
- Jiang, C., Hou, X., Wang, C., May, J. V., Butnev, V. Y., Bousfield, G. R., & Davis, J. S. 2015. Hypo-glycosylated hFSH has greater bioactivity than fully-glycosylated recombinant hFSH in human granulosa cells. J. Clin. Endocrinol. Metab., 100(6), e852-E860.
- Butnev, V. Y., Butnev, V. Y., May, J. V., Shuai, B., Tran, P., White, W. K., & Bousfield, G. R. Production, purification, and characterization of recombinant hFSH glycoforms for functional studies. Mol. Cell. Endocrinol., 405, 41-52.
- Davis, J. S., Kumar, T. R., May, J. V., & Bousfield, G. R. 2014. Naturally occurring follicle-stimulating hormone glycosylation variants. J. Glycomics Lipidomics, 4, e117.
- Bousfield, G.R., Butnev, V.Y., Butnev, V.Y., Hiromasa, Y., Harvey, D.J., & May, J.V. 2014. Hypo-glycosylated human follicle-stimulating hormone (hFSH21/18) is much more active in vitro than fully-glycosylated hFSH (hFSH24). Mol. Cell. Endocrinol., 382, 989-997.
- Alwis, I.D., Maroni, D.M., Hendry, I.R., Roy, S.K., May, J.V., Leavitt, W.W., & Hendry, W.J., 2011. Neonatal Diethylstilbestrol Exposure Disrupts Female Reproductive Tract Structure/Function Via Both Direct And Indirect Mechanisms In The Hamster. Reprod. Toxicol., 32(4), 472-483.
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Honors and Other Activities
Kansas-IDEA Network of Biomedical Research Excellence (K-INBRE): Faculty Scholar Award,
3/1/2007
NIH Study Section- Regular, 4-year Membership:
Previous - RAG, 10/15/2008 – 6/30/2012, extended through 2013
Previous - REB , 09/12/1994-06/30/1998
NIH Ad Hoc Member: RAG, 6/25-26/2007; ICER, 10/5-6/2006; CMIR, 6/21-22/2004; REB,
06/02-04/2003, 10/04-06/1993; 6/23-23/1993; BCE, 05/10-12/1992
NIH Special Study Sections: Cooperative Specialized Infertility Research Center Program
(U-54), NICHD, 4/8-11/1996; P-50 Site Visit Team DRG, NIH 9/28-30/1995; Special Emphasis
Panel, NICHD, NIH, 4/24/1998; Special Emphasis Panel, CSR, NIH, SBIR/STTR Grant Review,
3/29-30/1999 and 11/15-16/1999, Special Emphasis Review Panel, K08 grant review, 7/31/2002.
NIH Ad Hoc Grant Reviewer: MABS, 3/2005, 10/2005, 10/2006; EMNR-A02M, 10/2005; BCE,
12/1989, 5/1991.
Grant Reviewer: USDA 04/1990, 05/1991; and NSF 09/19/90.
Editorial Board: Endocrinology 1993-1996; American Journal of Physiology (Endocrinology/Metabolism)
1995-1997, 1998-2002
Consultant: Food and Drug Administration, DHHS, Ob/Gyn Devices Panel, 1996-2004
High Complexity Clinical Lab Director (HCLD) The American Board of Bioanalysis, 1994-2000
Laboratory Inspector, Reproductive Accreditation Program, College of American Pathologists,
1993-1996
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Courses Taught Previously
| BIOL 210 | General Biology I |
| BIOL 420 | Molecular Cell Biology |
| BIOL 526 | Endocrinology |
| BIOL 540 | Developmental Biology |
| BIOL 590 | Immunobiology |
| BIOL 626/640 | Reproductive Biology |