PDF
…response
to PA when CMG2 is bound is caused by CMG2 blocking a key epitope or epitopes within Domain
4. As such, removal of Domain 4 should elicit a significantly weaker immune response compared to a
full-length PA; that is, the majority of the immune response to PA is because of Domain 4.
Passion, Plan, & Pursue
49
Research Sammaries
Methods…
https://www.wichita.edu/_archive/services/mcnair/Journals/Volume26Journal20-21.pdf